Unsere Ärztliche Leitungen

Kliniken Schmieder Allensbach

Ärztliche Leitung Neurorehabilitation

Prof. Dr. med. Joachim Liepert
Sekretariat: Simone Biethinger
Tel.: 07533 808-1236
Zur Person Prof. Dr. med. Joachim Liepert

Qualifikationen:
Facharzt für Neurologie, Zusatzbezeichnungen „Spezielle Neurologische Intensivmedizin" und „Physikalische Therapie", Ausbildungsberechtigungen für Klinische Elektroenzephalographie und Evozierte Potentiale sowie für Klinische Elektromyographie.

Tätigkeitsschwerpunkte:
Schlaganfallrehabilitation mit Einsatz innovativer Therapiestrategien, Klinische Elektrophysiologie, Bewegungsstörungen sowie Botulinumtoxin-Behandlungen

Forschungsbereiche:
Plastizität des motorischen Systems, Rehabilitation-induzierte Reorganisation des Gehirns, senso-motorische Interaktionen, Elektrophysiologische Korrelate bei Fatigue u.a.

Verbandstätigkeit:
Deutsche Gesellschaft für Neurologie, Deutsche Gesellschaft für Klinische Neurophysiologie und funktionelle Bildgebung, Arbeitskreis „Botulinumtoxin", Deutsche Gesellschaft für Neurologische Rehabilitation

Preise:
1999: Poster-Preis der Deutschen Gesellschaft für Neurologie; 2005: Dozent des Jahres an der Universitätsklinik Hamburg-Eppendorf

Publikationen (Aktuelle Auswahl):
Using an upper extremity exoskeleton for semi-autonomous exercise during inpatient neurological rehabilitation- a pilot study. Büsching I, Sehle A, Stürner J, Liepert J. J Neuroeng Rehabil. 2018 Aug 2;15(1):72. doi: 10.1186/s12984-018-0415-6.

Reliability, validity, and clinical feasibility of a rapid and objective assessment of post-stroke deficits in hand proprioception. Rinderknecht MD, Lambercy O, Raible V, Büsching I, Sehle A, Liepert J, Gassert R. J Neuroeng Rehabil. 2018 Jun 7;15(1):47. doi: 10.1186/s12984-018-0387-6.

Passive repetitive sensible elektrische Stimulation zur Verbesserung motorischer Funktionen nach Schlaganfall – eine Pilotstudie A. Sehle1, I. Büsching1, H. R. Dinse2,3, J. Liepert Neurol Rehabil 2017; 23(1)

Assessing Anosognosia in Apraxia of Common Tool-Use With the VATA-NAT. Buchmann I, Jung R, Liepert J, Randerath J. Front Hum Neurosci. 2018 Mar 27;12:119. doi: 10.3389/fnhum.2018.00119

Mental contrasting with implementation intentions (MCII) improves physical activity and weight loss among stroke survivors over one year. Marquardt MK, Oettingen G, Gollwitzer PM, Sheeran P, Liepert J. Rehabil Psychol. 2017 Nov;62(4):580-590. doi: 10.1037/rep0000104

Symptom-specific amygdala hyperactivity modulates motor control network in conversion disorder. Hassa T, Sebastian A, Liepert J, Weiller C, Schmidt R, Tüscher O. Neuroimage Clin. 2017 Apr 27;15:143-150. doi: 10.1016/j.nicl.2017.04.004

Motor Imagery Impairment in Postacute Stroke Patients. Braun N, Kranczioch C, Liepert J, Dettmers C, Zich C, Büsching I, Debener S. Neural Plast. 2017;2017:4653256. doi: 10.1155/2017/4653256.

Age-based model for metacarpophalangeal joint proprioception in elderly. Rinderknecht MD, Lambercy O, Raible V, Liepert J, Gassert R. Clin Interv Aging. 2017 Apr 6;12:635-643. doi: 10.2147/CIA.S129601

Sehle A, Büsching I, Vogt E, Liepert J: Temporary deafferentation evoked by cutaneous anesthesia: behavioral and electrophysiological findings in healthy subjects. In: J Neural Transm (Vienna). 2016 May, 123 (5): 473-80. doi: 10.1007/s00702-016-1537-2.

Schönfeldt-Lecuona C, Lefaucheur JP, Lepping P, Liepert J, Connemann BJ, Sartorius A, Nowak DA, Gahr M: Non-Invasive Brain Stimulation in Conversion (Functional) Weakness and Paralysis: A Systematic Review and Future Perspectives. In: Front Neurosci. 2016 Mar 31; 10: 140. doi: 10.3389/fnins.2016.00140.

Dettmers C, Braun N, Büsching I, Hassa T, Debener S, Liepert J: Neurofeedback-based motor imagery training for rehabilitation after stroke. In: Der Nervenarzt. 2016 Oct, 87 (10): 1074-1081.

Liepert J: Drugs for improvement of motor deficits after stroke. In: Der Nervenarzt. 2016 Oct, 87 (10): 1082-1085.

Liepert J, Büsching I, Sehle A, Schoenfeld MA: Mental chronometry and mental rotation abilities in stroke patients with different degrees of sensory deficit. In: Restor Neurol Neurosci. 2016 Nov 22, 34 (6): 907-914.

Liepert J: Update on pharmacotherapy for stroke and traumatic brain injury recovery during rehabilitation. In: Curr Opin Neurol. 2016 Dec, 29 (6): 700-705.

Liepert J, Breitenstein C: New aspects of neurorehabilitation: motor and language. In: Der Nervenarzt. 2016 Nov 17. [Epub ahead of print]

Liepert J, Heller A, Behnisch G, Schoenfeld A: Polymorphism of brain derived neurotrophic factor and recovery of functions after ischemic stroke. In: Nervenarzt. 2015 Oct; 86 (10): 1255-60.

Liepert J, Shala J, Greiner J: Electrophysiological correlates of disobedience and feigning-like behaviour in Motor imagery. In: Clin Neurophysiol. 125 (4):763-7. doi: 10.1016/j.clinph.2013.09.013.

Liepert J, Greiner J, Dettmers C: Motor excitability changes during action observation in stroke patients. In: J Rehabil Med. 46 (5):400-5. doi: 10.2340/16501977-1276.

Ärztliche Leitung Akutneurologie

Prof. Dr. med. Anastasios Chatzikonstantinou, MBA
Sekretariat: Ramona Nitsch
Tel.: 07533 808-1376
Zur Person Prof. Dr. med. Anastasios Chatzikonstantinou, MBA

Qualifikationen:
Facharzt für Neurologie, Zusatzbezeichnung Intensivmedizin, Zertifikat für Epileptologie (DGfE), Zertifikat für Elektroenzephalographie (DGKN), Zertifikat für Evozierte Potentiale (DGKN), Master of Business Administration

Tätigkeitsschwerpunkte:
Gesamtes Spektrum der Akutversorgung neurologischer Erkrankungen, Schlaganfall, Epilepsie, Parkinson

Forschungsbereiche:
Epilepsie, Schlaganfall, Elektrophysiologie

Verbandstätigkeit:
Deutsche Gesellschaft für Neurologie, Deutsche Gesellschaft für Klinische Neurophysiologie und funktionelle Bildgebung, Deutsche Schlaganfall-Gesellschaft, Deutsche Gesellschaft für Epileptologie

Publikationen:
Chatzikonstantinou A. Pharmakotherapie des Status epilepticus. Medikamentöse Optionen in den verschiedenen Phasen des Status epilepticus. Arzneimitteltherapie 2020;38:183-95.
 
Wolf ME, Ebert AD, Chatzikonstantinou A. The use of routine EEG in acute ischemic stroke patients without seizures: generalized but not focal EEG pathology is associated with clinical deterioration. Int J Neurosci. 2017 May;127(5):421-426. doi: 10.1080/00207454.2016.1189913. Epub 2016 Jun 1. PubMed PMID: 27180832.
 
Kelly PJ, Albers GW, Chatzikonstantinou A, De Marchis GM, Ferrari J, George P, Katan M, Knoflach M, Kim JS, Li L, Lee EJ, Olivot JM, Purroy F, Raposo N, Rothwell PM, Sharma VK, Song B, Tsivgoulis G, Walsh C, Xu Y, Merwick A. Validation and comparison of imaging-based scores for prediction of early stroke risk after transient ischaemic attack: a pooled analysis of individual-patient data from cohort studies. Lancet Neurol. 2016 Nov;15(12):1238-1247. doi: 10.1016/S1474-4422(16)30236-8. Epub 2016 Oct 11. PubMed PMID: 27751555.
 
Sauer T, Wolf ME, Ebert AD, Szabo K, Chatzikonstantinou A. Vertebral Artery Hypoplasia Does Not Influence Lesion Size and Clinical Severity in Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2016 Jul;25(7):1770-1775. doi: 10.1016/j.jstrokecerebrovasdis.2016.03.050. Epub 2016 Apr 18. PubMed PMID: 27103271.
 
Chatzikonstantinou A, Ebert AD, Wolf ME. The Impact of Body Mass Index on the  Thrombolytic Treatment of Acute Ischemic Stroke. Cerebrovasc Dis. 2016;42(3-4):240-6. doi: 10.1159/000446005. Epub 2016 May 14. PubMed PMID: 27173490.
 
Wolf ME, Alonso A, Ebert AD, Szabo K, Chatzikonstantinou A. Etiologic and Clinical Characterization of Patients with Recurrent Spontaneous Intracerebral Hemorrhage. Eur Neurol. 2016;76(5-6):295-301. Epub 2016 Nov 3. PubMed PMID: 27806359.
 
Wolf ME, Chatzikonstantinou A, Grüttner J, Ebert AD, Walter T, Hennerici MG, Fatar M. Is It Acute Stroke or Not - A Prospective Observational Study from a Multidisciplinary Emergency Department. Eur Neurol. 2016;75(3-4):170-7. doi: 10.1159/000445249. Epub 2016 Apr 1. PubMed PMID: 27031948.
 
Chatzikonstantinou A, Ebert AD, Hennerici MG. Cerebrospinal fluid findings after epileptic seizures. Epileptic Disord. 2015 Dec;17(4):453-9. doi: 10.1684/epd.2015.0779. PubMed PMID: 26575850.
 
Chatzikonstantinou A, Ebert AD, Hennerici MG. Temporal seizure focus and status epilepticus are associated with high-sensitive troponin I elevation after epileptic seizures. Epilepsy Res. 2015 Sep;115:77-80. doi: 10.1016/j.eplepsyres.2015.05.013. Epub 2015 Jun 2. PubMed PMID: 26220381.
 
Chatzikonstantinou A, Ebert AD, Schoenberg SO, Hennerici MG, Henzler T. Atherosclerosis in intracranial, extracranial, and coronary arteries with aortic plaques in patients with ischemic stroke of undetermined etiology. Int J Neurosci. 2015;125(9):663-70. doi: 10.3109/00207454.2014.961188. Epub 2014 Sep 30. PubMed PMID: 25180988.
 
Chatzikonstantinou A. Epilepsy and the hippocampus. Front Neurol Neurosci. 2014;34:121-42. doi: 10.1159/000356435. Epub 2014 Apr 16. Review. PubMed PMID: 24777136.
 
Wolf ME, Sauer T, Hennerici MG, Chatzikonstantinou A. Characterization of patients with recurrent ischaemic stroke using the ASCO classification. Eur J Neurol. 2013 May;20(5):812-7. doi: 10.1111/ene.12068. Epub 2013 Jan 8. PubMed PMID: 23293855.
 
Chatzikonstantinou A, Wolf ME, Schaefer A, Hennerici MG. Risk prediction of subsequent early stroke in patients with transient ischemic attacks. Cerebrovasc Dis. 2013;36(2):106-9. doi: 10.1159/000352060. Epub 2013 Sep 11. PubMed PMID: 24029463.
 
Chatzikonstantinou A, Wolf ME, Hennerici MG. Ischemic stroke in young adults: classification and risk factors. J Neurol. 2012 Apr;259(4):653-9. doi: 10.1007/s00415-011-6234-3. Epub 2011 Sep 17. PubMed PMID: 21927959.
 
Chatzikonstantinou A, Krissak R, Flüchter S, Artemis D, Schaefer A, Schoenberg SO, Hennerici MG, Fink C. CT angiography of the aorta is superior to transesophageal echocardiography for determining stroke subtypes in patients with cryptogenic ischemic stroke. Cerebrovasc Dis. 2012;33(4):322-8. doi: 10.1159/000335828. Epub 2012 Feb 15. PubMed PMID: 22343088.
 
Chatzikonstantinou A, Krissak R, Schaefer A, Schoenberg SO, Fink C, Henneric MG. Coexisting large and small vessel disease in patients with ischemic stroke of undetermined cause. Eur Neurol. 2012;68(3):162-5. Epub 2012 Aug 14. PubMed PMID: 22906845.
 
Chatzikonstantinou A, Wolf ME, Schaefer A, Hennerici MG. Asymptomatic and symptomatic carotid stenosis: an obsolete classification? Stroke Res Treat. 2012;2012:340798. doi: 10.1155/2012/340798. Epub 2012 Jan 23. PubMed PMID: 22315705; PubMed Central PMCID: PMC3270474.
 
Chatzikonstantinou A, Gass A, Förster A, Hennerici MG, Szabo K. Features of acute DWI abnormalities related to status epilepticus. Epilepsy Res. 2011 Nov;97(1-2):45-51. doi: 10.1016/j.eplepsyres.2011.07.002. Epub 2011 Jul 28. PubMed PMID: 21802259.
 
Chatzikonstantinou A, Förster A, Hennerici MG, Bäzner H. From the stroke unit to the stroke competence center: corresponding beneficial clinical and financial effects. J Neurol. 2011 Nov;258(11):1929-32. doi: 10.1007/s00415-011-6032-y. Epub 2011 Apr 6. PubMed PMID: 21625936.
 
Chatzikonstantinou A, Willmann O, Szabo K, Hennerici MG. Cerebral microbleeds are uncommon in ischemic stroke associated with nonvalvular atrial fibrillation. J Neuroimaging. 2011 Apr;21(2):103-7. doi: 10.1111/j.1552-6569.2009.00440.x. PubMed PMID: 19888932.

Ärztliche Leitung Neuroradiologie und Radiologie

Prof. Dr. med. Christoph Stippich
Sekretariat: Simone Biethinger
Tel.: 07533 808-1236 // 0151 74460854
Zur Person Prof. Dr. med. Christoph Stippich

Qualifikationen:
Facharzt für Diagnostische Radiologie (D), Radiologie (CH, FMH), Schwerpunktanerkennungen: Neuroradiologie (D), Diagnostische Neuroradiologie (CH), Invasive Neuroradiologie (CH), Ärztliches Qualitätsmanagement (D)

Tätigkeitsschwerpunkte:
Gesamtes Spektrum der Neuroradiologie, Neurovaskuläre, onkologische und neurodegenerative Erkrankungen, Multiple Sklerose, Hirntumore, Demenz

Forschungsbereiche:
Bildgebung von Hirnfunktionen und Struktur

Verbandstätigkeit:
Deutsche Röntgen-Gesellschaft, Schweizerische Gesellschaft für Radiologie, Neuroradiologie (SGNR), Schweizer Hirnschlaggesellschaft, Vize-Präsident der SGNR, Vorsitzender der Alpine-Chapter der Organisation for Human Brain Mapping (OHBM)

Publikationen:
Buch:: Clinical Functional MRI, Presurgical Functional Neuroimaging, Editors: Stippich, Christoph (Ed.), https://www.springer.com/gp/book/9783662451229

Endovascular therapy versus intravenous thrombolysis in cervical artery dissection ischemic stroke - Results from the SWISS registry.
Traenka C, Jung S, Gralla J, Kurmann R, Stippich C, Simonetti BG, Gensicke H, Mueller H, Lovblad K, Eskandari A, Puccinelli F, Vehoff J, Weber J, Wegener S, Steiner L, Kägi G, Luft A, Sztajzel R, Fischer U, Bonati LH, Peters N, Michel P, Lyrer PA, Arnold M, Engelter ST.
Eur Stroke J. 2018 Mar;3(1):47-56. doi: 10.1177/2396987317748545. Epub 2018 Jan 3.
PMID: 31008337 Free PMC article.

Relationships of Overt and Silent Brain Lesions With Cognitive Function in Patients With Atrial Fibrillation.
Conen D, Rodondi N, Müller A, Beer JH, Ammann P, Moschovitis G, Auricchio A, Hayoz D, Kobza R, Shah D, Novak J, Schläpfer J, Di Valentino M, Aeschbacher S, Blum S, Meyre P, Sticherling C, Bonati LH, Ehret G, Moutzouri E, Fischer U, Monsch AU, Stippich C, Wuerfel J, Sinnecker T, Coslovsky M, Schwenkglenks M, Kühne M, Osswald S; Swiss-AF Study Investigators.
J Am Coll Cardiol. 2019 Mar 12;73(9):989-999. doi: 10.1016/j.jacc.2018.12.039.
PMID: 30846109

Can We Standardize Clinical Functional Neuroimaging Procedures?
Beisteiner R, Pernet C, Stippich C.
Front Neurol. 2019 Jan 8;9:1153. doi: 10.3389/fneur.2018.01153. eCollection 2018.
PMID: 30671017 Free PMC article.

Structured Reporting in Neuroradiology: Intracranial Tumors.
Bink A, Benner J, Reinhardt J, De Vere-Tyndall A, Stieltjes B, Hainc N, Stippich C.
Front Neurol. 2018 Feb 6;9:32. doi: 10.3389/fneur.2018.00032. eCollection 2018.
PMID: 29467712 Free PMC article.

The Bright, Artificial Intelligence-Augmented Future of Neuroimaging Reading.
Hainc N, Federau C, Stieltjes B, Blatow M, Bink A, Stippich C.
Front Neurol. 2017 Sep 21;8:489. doi: 10.3389/fneur.2017.00489. eCollection 2017.
PMID: 28983278 Free PMC article.

Vascular Anatomy Predicts the Risk of Cerebral Ischemia in Patients Randomized to Carotid Stenting Versus Endarterectomy.
Müller MD, Ahlhelm FJ, von Hessling A, Doig D, Nederkoorn PJ, Macdonald S, Lyrer PA, van der Lugt A, Hendrikse J, Stippich C, van der Worp HB, Richards T, Brown MM, Engelter ST, Bonati LH.
Stroke. 2017 May;48(5):1285-1292. doi: 10.1161/STROKEAHA.116.014612. Epub 2017 Apr 11.
PMID: 28400487 Clinical Trial.

Presurgical motor, somatosensory and language fMRI: Technical feasibility and limitations in 491 patients over 13 years.
Tyndall AJ, Reinhardt J, Tronnier V, Mariani L, Stippich C.
Eur Radiol. 2017 Jan;27(1):267-278. doi: 10.1007/s00330-016-4369-4. Epub 2016 May 19.
PMID: 27193934

The Swiss Multiple Sclerosis Cohort-Study (SMSC): A Prospective Swiss Wide Investigation of Key Phases in Disease Evolution and New Treatment Options.
Disanto G, Benkert P, Lorscheider J, Mueller S, Vehoff J, Zecca C, Ramseier S, Achtnichts L, Findling O, Nedeltchev K, Radue EW, Sprenger T, Stippich C, Derfuss T, Louvion JF, Kamm CP, Mattle HP, Lotter C, Du Pasquier R, Schluep M, Pot C, Lalive PH, Yaldizli Ö, Gobbi C, Kappos L, Kuhle J; SMSC Scientific Board.
PLoS One. 2016 Mar 31;11(3):e0152347. doi: 10.1371/journal.pone.0152347. eCollection 2016.
PMID: 27032105 Free PMC article.

Neuropsychological Markers of Medial Perirhinal and Entorhinal Cortex Functioning are Impaired Twelve Years Preceding Diagnosis of Alzheimer's Dementia.
Hirni DI, Kivisaari SL, Krumm S, Monsch AU, Berres M, Oeksuez F, Reinhardt J, Ulmer S, Kressig RW, Stippich C, Taylor KI.
J Alzheimers Dis. 2016 Mar 26;52(2):573-80. doi: 10.3233/JAD-150158.
PMID: 27031465

Primary motor cortex activation and lateralization in patients with tumors of the central region.
Tozakidou M, Wenz H, Reinhardt J, Nennig E, Riffel K, Blatow M, Stippich C.
Neuroimage Clin. 2013 Jan 14;2:221-8. doi: 10.1016/j.nicl.2013.01.002. eCollection 2013.
PMID: 24179775 Free PMC article.

In volunteers the strongest activation is usually found in the M1 hand representation contralateral to the movement, while a weaker homotopic co-activation is observed in ipsilateral M1 (Stippich et al., 2007a). ...
Clinical standardized fMRI reveals altered language lateralization in patients with brain tumor.
Partovi S, Jacobi B, Rapps N, Zipp L, Karimi S, Rengier F, Lyo JK, Stippich C.
AJNR Am J Neuroradiol. 2012 Dec;33(11):2151-7. doi: 10.3174/ajnr.A3137. Epub 2012 May 17.
PMID: 22595902 Free article.

Diagnostic benefits of presurgical fMRI in patients with brain tumours in the primary sensorimotor cortex.
Wengenroth M, Blatow M, Guenther J, Akbar M, Tronnier VM, Stippich C.
Eur Radiol. 2011 Jul;21(7):1517-25. doi: 10.1007/s00330-011-2067-9. Epub 2011 Jan 28.
PMID: 21271252 Free PMC article.

Altered somatosensory processing in trigeminal neuralgia.
Blatow M, Nennig E, Sarpaczki E, Reinhardt J, Schlieter M, Herweh C, Rasche D, Tronnier VM, Sartor K, Stippich C.
Hum Brain Mapp. 2009 Nov;30(11):3495-508. doi: 10.1002/hbm.20773.
PMID: 19365802 Free PMC article.

Localizing and lateralizing language in patients with brain tumors: feasibility of routine preoperative functional MR imaging in 81 consecutive patients.
Stippich C, Rapps N, Dreyhaupt J, Durst A, Kress B, Nennig E, Tronnier VM, Sartor K.
Radiology. 2007 Jun;243(3):828-36. doi: 10.1148/radiol.2433060068.
PMID: 17517936 Clinical Trial.

Loss of anisotropy in trigeminal neuralgia revealed by diffusion tensor imaging.
Herweh C, Kress B, Rasche D, Tronnier V, Tröger J, Sartor K, Stippich C.
Neurology. 2007 Mar 6;68(10):776-8. doi: 10.1212/01.wnl.0000256340.16766.1d.
PMID: 17339587 Clinical Trial.

Motor, somatosensory and auditory cortex localization by fMRI and MEG.
Stippich C, Freitag P, Kassubek J, Sörös P, Kamada K, Kober H, Scheffler K, Hopfengärtner R, Bilecen D, Radü EW, Vieth JB.
Neuroreport. 1998 Jun 22;9(9):1953-7. doi: 10.1097/00001756-199806220-00007.
PMID: 9674573 Clinical Trial.

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